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Glove permeation of chemicals: The state of the art of current practice—Part 2. Research emphases on high boiling point compounds and simulating the donned glove environment

Pages 135-164
Published online: 25 Mar 2020


This second part of the review of the 21st century literature on glove permeation is divided into the following major themes; permeation data and mathematical models, exposure/risk assessment, and manufacturer data. The major issues in the literature were the demonstrations that increasing temperature and applying forces increased permeation; and that glove manufacturer data were sometimes not reproducible. Double gloving of disposable gloves was found to be effective in resisting chemical permeation for short periods of time. Harmonization of standards and commercial glove classifications were called for at conditions that were closer to the temperature and applied forces actually present in the workplace, including whole glove testing and quantitative rather than just qualitative criteria. More research was recommended in each section and subsection with particular emphasis on defining the efficiency of solid phase collection devices, and more data in areas like exposure to cosmetics, household products, liquid foods, drinks, and cleaning liquids. More research in exposure assessment for permeated chemicals with sensors on the inner glove surface and on the skin was called for. Finally, it was decided that the state of the art of current practice was in a situation that needed the permeation standards, research, and the permeation charts of glove manufacturers to be at conditions that better reflected those encountered by workers with donned gloves.


Thanks for the support of the UCLA Center for Occupational and Environmental Health, and the Southern California NIOSH Education and Research Center. Sean Banaee was partially supported by a Graduate Fellowship of the Southern California NIOSH Education and Research Center, Grant Agreement Number T42OH008412 from the Centers for Disease Control and Prevention (CDC). The contents are solely the responsibility of the authors and do not necessarily represent the official view of the CDC.


The authors deny conflict of interest in the present study.

Additional information


This research was funded by the UCLA Center for Occupational and Environmental Health and the Southern California NIOSH Education and Research Center, Grant Agreement Number T42OH008412.

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